Detalhe da pesquisa
1.
N-terminal domain antigenic mapping reveals a site of vulnerability for SARS-CoV-2.
Cell
; 184(9): 2332-2347.e16, 2021 04 29.
Artigo
em Inglês
| MEDLINE | ID: mdl-33761326
2.
Broad sarbecovirus neutralization by a human monoclonal antibody.
Nature
; 597(7874): 103-108, 2021 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-34280951
3.
SARS-CoV-2 RBD antibodies that maximize breadth and resistance to escape.
Nature
; 597(7874): 97-102, 2021 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-34261126
4.
Perturbation of Alphavirus and Flavivirus Infectivity by Components of the Bacterial Cell Wall.
J Virol
; 96(6): e0006022, 2022 03 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-35107376
5.
A SCID Mouse Model To Evaluate the Efficacy of Antivirals against SARS-CoV-2 Infection.
J Virol
; 96(16): e0075822, 2022 08 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-35924921
6.
A dual-antigen self-amplifying RNA SARS-CoV-2 vaccine induces potent humoral and cellular immune responses and protects against SARS-CoV-2 variants through T cell-mediated immunity.
Mol Ther
; 30(9): 2968-2983, 2022 09 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-35450821
7.
Favipiravir at high doses has potent antiviral activity in SARS-CoV-2-infected hamsters, whereas hydroxychloroquine lacks activity.
Proc Natl Acad Sci U S A
; 117(43): 26955-26965, 2020 10 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-33037151
8.
Insertion of an Amphipathic Linker in a Tetrapodal Tryptophan Derivative Leads to a Novel and Highly Potent Entry Inhibitor of Enterovirus A71 Clinical Isolates.
Int J Mol Sci
; 24(4)2023 Feb 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-36834952
9.
A novel druggable interprotomer pocket in the capsid of rhino- and enteroviruses.
PLoS Biol
; 17(6): e3000281, 2019 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-31185007
10.
Molnupiravir Inhibits Replication of the Emerging SARS-CoV-2 Variants of Concern in a Hamster Infection Model.
J Infect Dis
; 224(5): 749-753, 2021 09 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-34244768
11.
ALG-097111, a potent and selective SARS-CoV-2 3-chymotrypsin-like cysteine protease inhibitor exhibits in vivo efficacy in a Syrian Hamster model.
Biochem Biophys Res Commun
; 555: 134-139, 2021 05 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-33813272
12.
Multivalent Tryptophan- and Tyrosine-Containing [60]Fullerene Hexa-Adducts as Dual HIV and Enterovirus A71 Entry Inhibitors.
Chemistry
; 27(41): 10700-10710, 2021 Jul 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-33851758
13.
Novel Class of Chikungunya Virus Small Molecule Inhibitors That Targets the Viral Capping Machinery.
Antimicrob Agents Chemother
; 64(7)2020 06 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-32340991
14.
Understanding the Mechanism of the Broad-Spectrum Antiviral Activity of Favipiravir (T-705): Key Role of the F1 Motif of the Viral Polymerase.
J Virol
; 91(12)2017 06 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-28381577
15.
Discovery of novel multi-target indole-based derivatives as potent and selective inhibitors of chikungunya virus replication.
Bioorg Med Chem
; 25(1): 327-337, 2017 01 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-27856239
16.
Inhibition of Chikungunya Virus-Induced Cell Death by Salicylate-Derived Bryostatin Analogues Provides Additional Evidence for a PKC-Independent Pathway.
J Nat Prod
; 79(4): 680-4, 2016 Apr 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-26900711
17.
Simplified Bryostatin Analogues Protect Cells from Chikungunya Virus-Induced Cell Death.
J Nat Prod
; 79(4): 675-9, 2016 Apr 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-26900625
18.
Comparing the Infectivity of Recent SARS-CoV-2 Omicron Sub-Variants in Syrian Hamsters.
Viruses
; 16(1)2024 Jan 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-38257822
19.
Genetic consequences of effective and suboptimal dosing with mutagenic drugs in a hamster model of SARS-CoV-2 infection.
Virus Evol
; 10(1): veae001, 2024.
Artigo
em Inglês
| MEDLINE | ID: mdl-38486802
20.
Design, synthesis, and lead optimization of piperazinyl-pyrimidine analogues as potent small molecules targeting the viral capping machinery of Chikungunya virus.
Eur J Med Chem
; 264: 116010, 2024 Jan 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-38104375